sure,
put a smal textfile or json together with the setup on a server something like:
B4X:
[Version]
Version=3.6.4
DOR=21/01/2016
Filesize=5,5 MB
Whatsnew=Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmo
DownloadPath=
DownloadFile=setup.exe
CloseProgramBeforeUpdate=YES
then you get this file on the app start (httputils) and compare it with the installed app. If it is newer, you provide a dialog to the user, if he wants to update...