Super-minor point, more of interest than of real-life effect, but:
finding the midpoint by averaging coordinates is only precisely correct when either the line is on a meridian (north-south line), or on the equator, or equally north and south of the equator. But it's close enough. ? I often do worse when I assume a patch of earth is retangular rather than spherical.
Another super-minor point is that airplanes weigh less when flying east than when flying west, thanks to increased centrifugal effect.