You can define an Array for the B4XPlusMinus objects.
Example:
Private btnPlusMinus(13) As B4XPlusMinus
Private B4XPlusMinus1 As B4XPlusMinus
Private B4XPlusMinus2 As B4XPlusMinus
Private B4XPlusMinus3 As B4XPlusMinus
Private B4XPlusMinus4 As B4XPlusMinus
Private B4XPlusMinus5 As B4XPlusMinus
...
And in ActivityCreate:
btnPlusMinus = Array As B4XPlusMinus (B4XPlusMinus1, B4XPlusMinus2, B4XPlusMinus3, ...
Then you could go through the buttons in a For / Next loop like:
For i = 0 To btnPlusMinus.Length - 1
Next
Be aware that you have B4XPlusMinus2 and B4XPlusMinus2B, you need to know which index corresponds to which Button.
btnPlusMinus(0) is B4XPlusMinus1
btnPlusMinus(1) is B4XPlusMinus2
For your layouts, you should study
anchors.
This will save quite some Designer Scripts code.