This came up in another thread but I can't find it. It was mentioned that on occasion the abstract designer doesn't seem to automatically resize the layout to the currently selected layout variant.
There may be other times this happens (and perhaps this behavior is intentional) but I noticed it again today and made a note of what is happening.
Say I have two layouts, both with 2 variants. Variant 1 is 320x480 and the other is 480x320 (portrait and landscape). If I am on layout 1 and click on the landscape variant, the Abstract Designer changes to reflect it as expected. However, the glitch happens if I then choose another LAYOUT and the first variant in the list does not match the last one I was on. The only way to fix the issue is to choose another variant then go back to the original one.
I hope I explained this well.