It needs to google about lock bits (fuse bits) of the MCU. And how to program them in Arduino. Nothing ready about this in B4R directly.
I guess, a special USB-programmer dongle and official Atmel software tool may help to "burn" these fuses.
Search for "avrdude" CLI utility.
And initially make sure that the sketch development is fully finished, and you are ready to replace the wrongly fuse-programmed device (MCU).