I try to connect my Uno with a USB port via a virtuelle serial port. It seems to work but there is a red warning in the logs:
SLF4J: Failed to load class "org.slf4j.impl.StaticLoggerBinder".
SLF4J: Defaulting to no-operation (NOP) logger implementation
SLF4J: See http://www.slf4j.org/codes.html#StaticLoggerBinder for further details.